Hyaluronic Acid Matrix
Hyaluronic Acid Matrix is a highly refined formulation acting as the carrier base in AminoBox Polypeptide additives.
$24.00
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Product Data
Compound Identity
| Product Name | Hyaluronic Acid Matrix |
| Functional Class | Synthetics |
| Form | encapsulated |
| Purity | 99%+ |
| Content | 5mg |
| Count | 1 vial |
| Research Use | Research Grade |
Specifications
Technical Specs
| CAS Number | See COA |
| Molecular Weight | See COA |
| Molecular Formula | See COA |
| PubChem CID | See COA |
| Appearance | White to off-white powder |
| Storage | 2-8C preferred |
Product Specs
Solubility Profile
| Water | Highly soluble |
| Acidified Water | Highly soluble |
| DMSO | Highly soluble |
| Ethanol | Moderate |
| Lipid solvents | Poor compatibility |
Product Specs
Storage Specs
| Lyophilized | 2–8°C preferred |
| Long-term | −20°C recommended |
| Light Sensitivity | Moderate |
| Moisture | High sensitivity |
| Stability | Stable when dry |
| Container | Sterile sealed vial |
Literature
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Important Notice
Research Use Only
AminoBox products are supplied for research, analytical, and laboratory use only. Product information is provided for educational and technical reference and does not constitute medical advice. Products are not intended to diagnose, treat, cure, or prevent any disease.
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Chemical Specifications – Hyaluronic Acid matrix | 4 oz
| Specification | Details | Notes |
|---|---|---|
| Product Name | Hyaluronic Acid Serum (Base Formulation) | Cosmetic peptide carrier base |
| Primary INCI Name | Aqua (Water), Sodium Hyaluronate | HA in sodium salt form |
| Active Ingredient | Hyaluronic Acid (Sodium Hyaluronate) | Humectant polymer |
| Molecular Classification | Glycosaminoglycan (Polysaccharide) | Naturally occurring ECM component |
| Concentration Type | Multi-weight Hyaluronic Acid Blend | High + low molecular weight HA (typical cosmetic system) |
| Function | Hydration, moisture retention, viscosity support | Water-binding humectant system |
| Mechanism of Action | Binds and retains water within stratum corneum | Supports skin hydration matrix |
| pH Range | ~4.5 – 6.5 | Skin-compatible acidic range |
| Solubility | Fully water soluble | Compatible with peptide dilution |
| Appearance | Clear to slightly viscous gel/serum | Transparent formulation |
| Odor | Odorless | No added fragrance |
| Texture | Lightweight gel-serum base | Designed for layering actives |
| Viscosity System | Polymer-thickened aqueous gel base | Stabilizes peptide dispersion |
| Preservative System | Cosmetic-grade broad spectrum preservative | Prevents microbial growth |
| Stability | Stable under refrigeration or room temp storage | Avoid heat exposure |
| Storage Conditions | 15–25°C recommended, avoid direct sunlight | Refrigeration optional |
| Container Type | 4 oz (118 mL) cosmetic-grade jar | Wide-mouth for easy mixing |
| Closure Type | Screw-on lid | Airtight seal recommended |
| Material | HDPE or glass (batch dependent) | Glass preferred for peptide work |
| Compatibility | Peptides, vitamins, niacinamide, actives | Ideal carrier base |
| Intended Use | Cosmetic formulation base for peptide blending | Not a standalone drug product |
| Manufacturing Standard | Cosmetic GMP compliant production | Non-sterile cosmetic grade |
Custom Formulation Protocol
This Hyaluronic Acid Base Serum serves as the foundational carrier vehicle engineered specifically for the entire Aminobox cosmetic peptide portfolio.
- To prepare your custom active mixture, simply empty 100mg of your selected Aminobox peptide isolate directly into the 4oz container of serum base.
- Utilize the included custom spatula to stir the solution thoroughly, ensuring the raw crystalline structures completely dissolve and disperse evenly throughout the viscous matrix.
- This clean integration yields an optimized cosmetic active layer, structurally calculated to sustain consistent, high-density skin-conditioning performance for well over a month of daily deployment.
Molecular Mechanism of Action
Hyaluronic Acid (HA) is a naturally occurring glycosaminoglycan that serves as a fundamental structural component throughout the extracellular matrix (ECM) of human skin and connective tissues. Its primary physiological functions involve regulating fluid dynamics, providing viscoelastic structural support, and maintaining dermal hydration homeostasis. [1, 2, 3]
From a biochemical standpoint, hyaluronic acid functions as an exceptional humectant due to its highly hydrophilic nature, possessing the unique capacity to bind and retain water molecules up to 1,000 times its own molecular mass. [1, 2]
When integrated into sophisticated topical skincare applications, hyaluronic acid operates through several distinct pathways:
-
- Moisture Attraction: Draws atmospheric and trans-epidermal water molecules to the upper layers of the skin, increasing immediate hydration indices. [1, 2]
- Epidermal Reservoir Support: Facilitates the creation of a dense moisture-retention layer within the stratum corneum. [1, 2]
- Surface Textural Refinement: Improves visible skin smoothness, tactile softness, and surface elasticity by re-establishing optimal hydration levels. [1, 2]
- Volumetric Plumping: Temporarily reduces the visible depth and appearance of fine lines and wrinkles associated with dehydration. [1, 2]
- Barrier Function Reinforcement: Enhances epidermal resilience, stabilizing the natural moisture envelope to minimize trans-epidermal water loss (TEWL). [1, 2]
- Vehicle Performance: Optimizes formulation spreadability, providing an elegant cosmetic skin feel and acting as an excellent baseline carrier. [1, 2]
Biomimetic research confirms that endogenous hyaluronic acid levels decline progressively with age. This depletion is accelerated by environmental stressors, oxidative pathways, ultraviolet (UV) radiation, and enzymatic degradation, culminating in visible dryness, tissue laxity, and compromised barrier function. Topical HA applications are therefore widely utilized in cosmetic science to artificially restore hydration equilibrium and simulate optimal tissue vitality. [1, 2, 3]
Cosmetic Research Applications
This Hyaluronic Acid Base Serum is engineered as an adaptable matrix for formulation development, raw material testing, and advanced laboratory investigation involving:
Within professional laboratory settings, this aqueous hyaluronic matrix is favoured as a foundational carrier due to its exceptional biomimetic tolerance, physical stability, and neutral compatibility profile with a broad spectrum of cosmetic raw materials. [1, 2]
Peptide & Active Compatibility
The structural integrity of this serum base ensures high performance and stability when paired with advanced synthetic peptides, vitamins, and physiological lipids. Analytical data indicates specific compatibility with:
-
- SNAP-8 (Acetyl Octapeptide-3): An advanced peptide system targeting expression-associated fine lines.
- SYN-AKE® (Tripeptide-3): A specialized tripeptide utilized for skin smoothing and topical texture adjustment.
- SYN-COLL® (Palmitoyl Tripeptide-5): A biomimetic sequence focused on supporting structural matrix integrity.
- Melanostatine®-5 (Nonapeptide-1): A peptide asset researched for skin-brightening and tone-evening applications.
- Copper Peptides (GHK-Cu): An amino acid complex widely studied for its role in cellular repair and antioxidant defense.
- Matrixyl® Peptide Systems: Multi-chain signaling peptides utilized in premium anti-aging formulations.
- Vitamin Modulators: Universally compatible actives including Niacinamide (Vitamin B3) and Panthenol (Provitamin B5).
- Ceramide Complexes: Essential skin-identical lipids configured to repair lipid barrier matrices. [1, 2]
The lightweight, un-crosslinked aqueous architecture allows for seamless compounding with active molecules of varying molecular weights, including liposomal carriers, nanogel networks, and micro-emulsions to maximize chemical stability and skin conditioning performance. [1, 2, 3]
Formulation Logistics
- Texture Profile: Lightweight, fluid, and completely non-greasy; dries to a clean, invisible anchor layer with zero sticky residue.
- Absorption Track: Exhibits a fast dermal absorption profile, integrating cleanly with the skin surface within seconds of application.
- Blending Stability: Formulated to withstand broad pH variations and to serve as a stable suspension grid for hydrophilic macromolecules.
- Layering Versatility: Can be applied seamlessly beneath heavy lipid-based moisturizers, creams, or oils without pilling or separating. [1, 2, 3, 4, 5]
Scientific References – Hyaluronic Acid Serum (Sodium Hyaluronate Base)
| Title | Focus | Link |
|---|---|---|
| Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in Cosmetics | Overview of hyaluronic acid and sodium hyaluronate forms, hydration mechanisms, and cosmetic formulation use | https://pmc.ncbi.nlm.nih.gov/articles/PMC12731180/ |
| Sodium Hyaluronate (INCI Ingredient Profile) | Cosmetic ingredient profile covering structure, humectant function, and formulation applications | https://incibeauty.com/en/ingredients/19966-sodium-hyaluronate |
| Hyaluronic Acid and Its Salts in Skin Care Products | Review of HA derivatives (including sodium hyaluronate), water-binding properties, and skin hydration effects | https://www.specialchem.com/cosmetics/inci-ingredients/sodium-hyaluronate |
| Hyaluronic Acid: Structure, Properties, and Cosmetic Use | Scientific overview of HA as a glycosaminoglycan used in skincare and its role in dermal hydration | https://incibeauty.com/en/ingredients/462-hyaluronic-acid |
