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Methylene Blue – Raw Powder

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vial

1000mg

Raw powder (trihydrate)

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≥98% (USP-grade research)

$60.00

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  • By purchasing any products, you acknowledge and agree that all materials are supplied solely for scientific research, laboratory experimentation, or analytical purposes.
Form
raw_powder
Molecular Formula
C16H18ClN3S·3H2O
Molecular Weight
373.9 g/mol (trihydrate; anhydrous 319.9)
CAS Number
61-73-4 (anhydrous)
PubChem CID
6099
Research Data
Brain Activation (fMRI)
Rodriguez 2016 — peak fMRI response increase with low-dose MB
Literature
Cellular Ratio
Memory-Retrieval Accuracy
Rodriguez 2016 — change in correct memory-retrieval responses
Activity Profile
Research Application Profile
Mechanism
Cellular Pathway
01
Alternative Mitochondrial Electron Carrier
At low concentrations methylene blue cycles electrons directly to cytochrome c oxidase, supporting mitochondrial respiration and ATP production — the basis of its bioenergetic and neuroprotective research interest.
02
Hormetic Dose-Response
Effects are biphasic: low doses are stimulatory/antioxidant, while high doses become pro-oxidant and inhibitory — a narrow therapeutic window.
03
Established Clinical Use
Methylene blue is an FDA-recognized first-line antidote for acquired methemoglobinemia — its one well-established, high-evidence clinical use.
04
Evidence Caveats
Cognitive evidence is limited to small studies; tau-aggregation-inhibitor (LMTM) phase-3 Alzheimer’s trials did not meet primary endpoints. High-dose use carries serotonin-syndrome risk via MAO-A inhibition.
Metabolic Network
Biosynthesis Map
Alternative Mitochondrial Electron Carrier
At low concentrations methylene blue cycles electrons directly to…
Hormetic Dose-Response
Effects are biphasic: low doses are stimulatory/antioxidant, while high…
Established Clinical Use
Methylene blue is an FDA-recognized first-line antidote for acquired…
Evidence Caveats
Cognitive evidence is limited to small studies; tau-aggregation-inhibitor (LMTM)…
Repair Systems
Stress
Mitochondria
Energy
 METHYLENE BLUE RAW PO... CENTRAL HUB
Research Focus
Evidence Map by Application
Strength of evidence across methylene blue uses (0–100)
Product Data
Compound Identity
Product NameMethylene Blue (Raw Powder)
Functional ClassMitochondrial electron carrier / redox dye (methylthioninium)
Formraw_powder
Purity≥98% (USP-grade research)
Content1000mg
Count1 vial
Research UseFor Research Use Only. Not for human consumption, medical, veterinary, or household use.
Specifications
Technical Specs
CAS Number61-73-4 (anhydrous)
Molecular Weight373.9 g/mol (trihydrate; anhydrous 319.9)
Molecular FormulaC16H18ClN3S·3H2O
PubChem CID6099
AppearanceDark green crystalline powder (blue in solution)
StorageStore at room temperature, protected from light
Product Specs
Solubility Profile
WaterHighly soluble
Acidified WaterHighly soluble
DMSOHighly soluble
EthanolModerate
Lipid solventsPoor compatibility
Product Specs
Storage Specs
Lyophilized2–8°C preferred
Long-term−20°C recommended
Light SensitivityModerate
MoistureHigh sensitivity
StabilityStable when dry
ContainerSterile sealed vial
Literature
Research Citations
[1]Rodriguez P, et al. Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain. Radiology. 2016;281(2):516-526.
[2]Gauthier S, et al. Efficacy and safety of tau-aggregation inhibitor therapy (LMTM) in mild/moderate Alzheimer's disease: a phase 3 trial. Lancet. 2016;388(10062):2873-2884.
[3]PubChem Compound CID 6099 — Methylene blue (formula, mass, CAS 61-73-4).
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Important Notice
Research Use Only

AminoBox products are supplied for research, analytical, and laboratory use only. Product information is provided for educational and technical reference and does not constitute medical advice. Products are not intended to diagnose, treat, cure, or prevent any disease.